Organizational change - for example, the introduction of Agile practices - is like an infection. At first, the infection is localized and the body politic ignores it. Eventually and inevitably, the body politic will take notice, as its expectations and habits are disturbed. At that time, it will marshall its immune system and seek out and destroy the infectious change. IT management’s & business’s immune system is its governance processes. Unless governance processes and expectations are properly aligned with new agile and lean processes, agile and lean change will fail.